Peer-Reviewed Publications

Manuscripts

Up to date bibliography click here.

1.    Foster SL, Seehus C, Woolf CJ and Talbot S. Sense and immunity: Context-dependent neuro-immune interplay. Frontier in Immunology. Accepted. 

2.      Azimi E, Reddy VB, Pereira P, Talbot S, Woolf CJ and Lerner EA. Substance P activates Mrgprs to induce itch. Journal of Allergy and Clinical Immunology. 2017. S0091-6749(17)30230. PMID: 28219706

3.      Azimi E, Reddy VB, Shade KT, Anthony RM, Talbot S. Pereira P, and Lerner EA. Dual action of neurokinin-1 antagonists on Mas-related GPCRs. Journal of Clinical Investigation Insight. 2016. 1(16):e89362. PMID: 27734033.

 4.      Talbot S, Foster SL and Woolf CJ. Neuroimmunity: Physiology and Pathology. Annual Review of Immunology.  2016. 34:421-47. PMID: 26907213

5.      Hanes WM, Olofsson PS, Talbot S, Tsaava T, Ochani M, Imperato G, Levine YA, Roth J, Pascal MA, Foster SL, Wang P, Woolf CJ, Chavan SS, and Tracey KJ. Neuronal circuits modulate antigen flow through lymph nodes. Bioelectronic Medicine. 2016. 3:18-29  

6.      Talbot S, Dias JP, Midaoui AE, and Couture R. Beneficial effects of Kinin B1 receptor antagonism on plasma fatty acids alterations and overweight in Zucker diabetic fatty rats. Canadian Journal of Physiology and Pharmacology 2016. 94(7):752-7. PMID: 27172260

7.      Pereira PJ, Machado GD, Danesi GM, Canevese FF, Reddy VB, Pereira TC, Bogo MR, Cheng YC, Laedermann C, Talbot S, Lerner EA, Campos MM. GRPR/PI3Kγ: Partners in central transmission of itch. Journal of Neuroscience. 2015. 9;35(49):16272-81. PMID:26658875

8.      Talbot S, Abdulnour RE, Burkett PR. Lee S. Cronin SJ. Pascal MA. Leadermann C. Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Hehn CV, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VJ, Bean BP, Levy BD and Woolf CJ. Silencing nociceptor neurons reduces allergic airway inflammation. Neuron. 2015. 15;87(2):341-54. PMID:26119026

9.      Foster SL, Talbot S, Woolf CJ. CNS Injury: IL-33 sounds the alarm. Immunity. 2015. 17;42(3):403-5. PMID: 25786172

10.  Midaoui AE, Talbot S, Lahjouji K, Dias JP, Fantus, IG and Couture R. Effects of alpha-lipoic acid on oxidative stress and Kinin receptor expression in obese Zucker diabetic fatty rats. Journal of Diabetes and Metabolism. 2015. 1;6(6):1-7. PMID: 26413386

11.   De Brito Gariepy H, Talbot S, Sénécal J, Couture R. Brain Kinin B1 receptor contributes to the onset of stereotypic nocifensive behavior in rat. Behavioral Brain Research. 2013. 3;241C:17-26. PMID: 23219968

12.  Talbot S, De Brito Gariépy H, Saint-Denis J, Couture R. Activation of Kinin B1 receptor evokes hyperthermia through a vagal sensory mechanism in the rat. Journal of Neuroinflammation. 2012. 13;9:214. PMID: 22971439

13.  Pouliot M, Talbot S, Sénécal J, Dotigny F, Pruneau D, Vaucher E and Couture R. Ocular application of the Kinin B1 receptor antagonist LF22-0542 inhibits retinal inflammation and oxidative stress in Streptozotocin-diabetic rats. Plos One. 2012. 7(3):e33864. PMID: 22470485

14.  Talbot S, Dias JP, Lahjouji K, Bogo MR, Campos MM, Gaudreau P and Couture R.  Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia. Journal of Neuroinflammation. 2012. 20;9(1):16. PMID: 22264228 

15.  Lin JC, Roy JP, Verreault J, Talbot S, Côté F, Couture R, Morin A. An ex vivo approach to the differential parenchymal responses induced by cigarette whole smoke and its vapor phase. Toxicology.  2012. 11;293(1-3):125-31. PMID: 22266391

16.  Talbot S and Couture R. Emerging role of microglial kinin B1 receptor in diabetic pain neuropathy. Experimental Neurology. 2012. 234(2):373-81. PMID: 22154922

17.  Talbot S, Lin JC, Lahjouji K, Roy JP, Senecal J, Morin A and Couture R. Cigarette smoke-induced Kinin B1 Receptor promotes NADPH oxidase activity in cultured human alveolar epithelial cells. Peptides. 2011. 32(7):1447-56. PMID: 21600945

18.  Lin JC, Talbot S, Lahjouji K, Roy JP, Sénécal J, Couture R and Morin A. Mechanism of cigarette smoke-induced Kinin B1 Receptor expression in rat airways. Peptides. 2010. 31;(10):1940-5. PMID: 20637817

19.  Dias JP, Talbot S, Sénécal J, Carayon P and Couture R. Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications. Plos One. 2010. 7;5(9):e12622. PMID: 20830306

20.  Talbot S, Chahmi E, Pena PJ and Couture R. Key role for spinal dorsal horn microglial Kinin B1 receptor in early diabetic pain neuropathy. Journal of Neuroinflammation. 2010. 29;7(1):36. PMID: 20587056

21.  Talbot S, Theberge-Turmel P, Liazoghli D, Senecal J, Gaudreau P and Couture R. Cellular localization of Kinin B1 receptor in the spinal cord of Streptozotocin-diabetic rats with a fluorescent agonist, [Nα-Bodipy]-des-Arg9-bradykinin. Journal of Neuroinflammation. 2009. 26;6(1):11. PMID: 19323833

22.  Richard C, Lauzier B, Delemasure S, Talbot S, Ghibu S, Collin B, Sénécal J, Menetrier F, Vergely C, Couture R and Rochette L. Effects of angiotensin-1 converting enzyme inhibition on oxidative stress and bradykinin receptor expression during doxorubicin-induced cardiomyopathy in rats. Journal of Cardiovascular Pharmacology. 2008. 52(3):278-85. PMID: 18806609

23.  Ismael MA, Talbot S, Carbonneau CL, Beauséjour CM and Couture R. Blockade of sensory abnormalities and Kinin B1 receptor expression by N-Acetyl-L-Cysteine and ramipril in a rat model of insulin resistance. European Journal of Pharmacology. 2008. 28;589(1-3):66-72. PMID: 18555989

24.  Abdouh M, Talbot S, Couture R and Hasséssian HM. Retinal plasma extravasation in Streptozotocin-diabetic rats mediated by Kinin B1 and B2 receptors. British Journal of Pharmacology. 2008. 154(1):136-43. PMID: 18311190 

25.  Gallant MA, Slipetz D, Hamelin E, Rochdi MD, Talbot S, de Brum-Fernandes AJ and Parent JL. Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2. European Journal of Pharmacology. 2007. 28;557(2-3):115-23. PMID: 17207480

 


BOOK CHAPTER

1. Talbot S, Lin JC and Couture R. Kinin receptors. 2nd Edition - Handbook of Biologically Active Peptides. 2012. Boston: Academic Press.


BOOK

1. Talbot S. Localisation, mécanisme d’induction et rôle physiopathologique du récepteur B1 des kinines dans de modèles expérimentaux de douleur chez le rat. Éditions Universitaires Européennes. Germany. Accepted for publication. June 2017


PATENT

United States Patent and Trademark Office                                       Octroy: 2016/08/03

Charged ion channel blockers and methods for use. United States. PCT/US16/45354.

Inventors: Woolf CJ, Bean B, Talbot S, Lee J, Roberson D.


Published

Abstracts

A)    Oral presentations

 1.      Pereira PJ, Barroso G, Danesi GM, Canevese FF, Reddy V, Talbot S, Campos MM and Lerner E. Spinal PI3K-gamma activation mediates GRPR-related itching transmission in mice. 65thAnnual Montagna Symposium on the Biology of Skin. October 20-24th 2016. Gleneden Beach, USA

2.      Chahmi E, Talbot S, Dias JP and Couture R. Rôle et localisation intraspinale du récepteur B1 des kinines dans la douleur neuropathique. 52e Réunion du Club de Recherches Cliniques du Québec. September 23-25th 2010. Bromont, Canada (PIN: 79)

3. Pruneau D, Pouliot M, Talbot S, Vaucher E, Sahel JA, Combal JP, Latour E, Bemelmans A and Couture R. Kinin B1 receptor blockade: a promising treatment of diabetic retinopathy. 5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: session III)

4.      Talbot S, Dias JP and R Couture. Induction du récepteur B1 des kinines par la stimulation du TRPV1: Évidences moléculaires et pharmacologiques. 50e Réunion du Club de Recherches Cliniques du Québec. October 2-4th 2008. La Malbaie, Canada

5.      Talbot S, Ismael MA and Couture R. Blockade of sensory abnormalities and kinin B1 receptor expression by N-Acetyl-L-Cysteine and Ramipril in a rat model of insulin resistance. Canadian Diabetes Association. October 15-18th 2008. Montréal, Canada. Canadian Journal of Diabetes. 2008. 32(4)309

6.      Dias JP, Talbot S, Pilon M, Sénécal J, de Champlain J and Couture R. Le récepteur B1 des kinines comme cible thérapeutique dans le traitement du diabète. 3rd Annual GRUM meeting. May 29-30th 2008. Montréal, Canada

7.      Delemasure S, Talbot S, Sénécal J, Lauzier B, Beausejour CM, Vergely C, de Champlain J, Rochette L and R. Couture. Modulation of B1 and B2 kinin receptors during acute anthracyclines-induced cardiotoxicity in mice. Congrès de la société Française de Physiologie, de Pharmacologie et de Thérapeutique. April 9-11th 2008. Clermont-Ferrand, France

8.      Couture R, Dias JP, de Brito Pereira H, Talbot S, Ongali B, Carayon P and Ferrari B. Targeting kinin B1 receptors in hypertension and diabetes. 2nd International conference on hypertension, lipids, diabetes and stroke prevention. March 6-8th 2008. Prague, Czech Republic

B) Posters

 1.      Foster SL, Borriello F, Dutton A, Merrison H, Doyle B, Talbot S, Ceehus S, Dowling D, Levy O and Woolf CJ. Nociceptive neurons are activated by adjuvants or adjuvanted vaccines and may contribute to shaping antigen-specific humoral immune responses. 1st International Precision Vaccine Conference. October 23-24th, Boston. USA

2.      Talbot S. Direct allergen detection by vagal sensory neurons. Cell Symposium: Neuro-Immune Axis: Reciprocal Regulation in Development, Health, & Disease. September 17-19th 2017. Sitges, Spain. PIN : P1.23.

3.      Korecka JA, Talbot S, De Leeuw SM, Levy S, Ferrari EJ, Barret L, Dinesh D, Jodelka FM, Osborn TM, Woolf CJ, Hastings ML, Isacson O. LRRK2 G2019S mutation modulates intracellular and ER calcium homeostasis in human iPSC-derived neurons. 47th Annual Meeting of Society for Neuroscience. November 11-15th 2017. San Diego, USA.

4.      Mathur S, Foster SL, Seehus C, Talbot S, Woolf CJ. Role of Nociceptors in Driving B Cell Antibody Class Switching in Allergic Inflammation. 47th Annual Meeting of Society for Neuroscience. November 11-15th 2017. San Diego, USA.

 5.      Talbot S, Foster SL, Pascal MA, Chang RB, Parrin A, Doyle B, Lai N, Laedermann C, Abdulnour R, Latremoliere A, Browne L, Liberles SD, Bean BP, Levy BD and Woolf CJ. Airway nociceptors: Allergen sensing and reflex responses. 46th Annual Meeting of Society for Neuroscience. November 12-16th 2016. San Diego, USA (PIN: 445.13)

 6.      Korecka JA, Talbot S, Levy S, De Leeuw SM, Terpstra ML, Osborn TM, Hallett PJ, Jodelka FM, Woolf CJ, Hastings ML, Isacson O. Dysregulation of ER stress response and calcium homeostasis in human iPSC-derived neurons carrying the LRRK2 G2019S mutation. 46th Annual Meeting of Society for Neuroscience. November 12-16th 2016. San Diego, USA (PIN: 581.23)

7.      Foster S, Talbot S, Woolf CJ. Nociceptive Neurons Differentially Drive Type I and Type II Allergic Airway Inflammation. Journal of Women’s Health. 2016. 25 (9), 961-962

8.      Pereira PJ, Barroso G, Danesi GM, Canevese FF, Reddy V, Talbot S, Campos MM and Lerner E. Gastrin-releasing peptide receptor and PI3K-gamma are partners in the transmission of itch. 75th Annual Meeting of Society for Investigative Dermatology. May 11-14th 2016. Scottsdale, USA. Journal of Investigative Dermatology. 2016. 136 (5) Supplement 1. Page S87

9.      Pereira PJ, Barroso G, Danesi G, Canevese F, Reddy V, Talbot S, Campos MM and Lerner E. Spinal PI3K-gamma activation mediates GRPR-related itching transmission in mice. 8th World Congress on Itch. September 27- 29th 2015. Nara, Japan. Acta Dermatology Venereology. 2015. 95: 875–912

10.  Talbot S, Garyépy H and Couture R. La stimulation du récepteur B1 des kininesInduit une hyperthermie transitoire chez le rat.  52e Réunion du Club de Recherches Cliniques du Québec. September 22-24th 2011. Mont Gabriel, Canada

11.  Talbot S, de Brito Gariépy H and Couture R. New insight on thermoregulation through kinin. 40th Annual Meeting of Society for Neuroscience. November 13-17th 2010. San Diego, USA (PIN: 879.3)

12.  de Brito Gariepy H, Talbot S and Couture R.  Nocifensive behavioral reactions induced by activation of brain kinin B1 receptor in hypertensive rats. 40th Annual Meeting of Society for Neuroscience. November 13-17th 2010. San Diego, USA (PIN: 693.8)

13.  Talbot S, Dias JP, and Couture R. Induction of kinin B1 receptor by stimulation of TRPV1. 16th World Congress of Basic and Clinical Pharmacology. July 17-23th 2010. Copenhagen, Denmark (PIN: Thu073). Basic & Clinical Pharmacology & Toxicology, 2010. 107(606)

14.  Talbot S, de Brito Gariépy H and Couture R. New roles for kinin B1 receptor in the control of core temperature. 16th World Congress of Basic and Clinical Pharmacology. July 17-23th 2010. Copenhagen, Denmark. Basic & Clinical Pharmacology & Toxicology, 2010. 107(606)

15.  Pouliot M, Talbot S, Vaucher E, Pruneau D and Couture R. Topical administration of kinin B1 receptor antagonist, FV-60135-02, inhibits retinal inflammation in streptozotocin-diabetic rats. Association for Research in Vision and Ophthalmology. May 2-6th 2010. Fort Lauderdale, USA (PIN: 5611/D732). Investigative Ophthalmology & Visual Science. 2010. 51(13)5611

16.  Pruneau D, Pouliot M, Talbot S, Vaucher E, Provost A, Combal JP, Thomasson N, Bélichard P, Sahel JA and Couture R. Topical Treatment with the kinin B1 receptor antagonist, FV-60135-02, inhibits diabetic retinopathy in rats. Association for Research in Vision and Ophthalmology. May 2-6th 2010. Fort Lauderdale, USA (PIN: 117/A245). Investigative Ophthalmology & Visual Science. 2010. 51(13) 117

17.  Richard C, Lauzier B, Delemasure S, Talbot S, Ghibu S, Collin B, Sénécal J, Vergely-Vandriesse C, Couture R and Rochette L. Effects of Angiotensin-1 Converting Enzyme inhibition on oxidative stress and bradykinin receptor expression during doxorubic in-induced cardiomyopathy in rats. Archives of Cardiovascular Diseases Supplements. 2010. 2(1)85

18.  Talbot S, Chahmi E, Dias JP, Gaudreau P and Couture R. Key role for spinal dorsal horn microglial kinin B1 receptor in early diabetic pain neuropathy. 39th Annual Meeting of Society for Neuroscience. October 17-21th 2009, Chicago, USA (PIN: 561.9)

19.  Pouliot M, Talbot S, Vaucher E, Pruneau D and Couture R. L'administration topique de l'antagoniste du récepteur B1 des kinines FV-60135-02 inhibe l'inflammation de la rétine chez le rat diabétique. 51e Réunion du Club de Recherches Cliniques du Québec. 24-26th September 2009. Lac Delage, Canada (PIN: 50)

20.  Talbot S, Chahmi E, Dias JP, Gaudreau P and Couture R. Rôle clé du récepteur B1 microglial dans les neuropathies diabétiques. 51e Réunion du Club de Recherches Cliniques du Québec. September 24-26th 2009. Lac Delage, Canada (PIN: 100)

21.  Talbot S, Chahmi E, Dias JP and Couture R. Key role for spinal microglial kinin B1 receptor in diabetic pain neuropathy. 5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: P29)

22.  Dias JP, Talbot S, Pilon M, Sénécal J, de Champlain J, Ferrari B, Carayon P and Couture R. Kinin B1 receptor as a therapeutic target in the treatment of diabetes. 5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: P28)

23.  de Brito Pereira H, Talbot S and Couture R. The anti-hypertensive effect of kinin B1 receptor antagonists in two rat models of hypertension. 5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: P9)

24.  Pouliot M, Talbot S, Vaucher E, Pruneau D and Couture R. Topical administration of kinin B1 receptor antagonist fv-60135-02 inhibits retinal inflammation in streptozotocin-diabetic rats. 5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: P31)

25.  Tidjane N, Talbot S, Girolami JP and Couture R. Kinin B1 receptor as a therapeutic target in septic shock and diabetes.  5th International symposium on peptide receptors. June 26-30th 2009. Québec, Canada (PIN: P27)

26.  Talbot S, Dias JP and Couture R. Induction of Kinin B1 receptor by stimulation of TRPV1: molecular and pharmacological evidence. 38th Annual Meeting of Society for Neuroscience. November 15-19th 2008. Washington, USA

27.  de Brito Pereira H, Talbot S, Ongali B and Couture R. Role of B1 receptor in the central autonomic of blood pressure and body temperature in two rat models of hypertension. 38th Annual Meeting of Society for Neuroscience. November 15-19th 2008. Washington, USA

28.  Dias JP, Talbot S, Pilon M, Sénécal J, de Champlain J and Couture R. Kinin B1 receptor as therapeutics target for diabetes treatment. Canadian Diabetes Association. October 15-18th 2008. Montréal, Canada

29.  Richard C, Lauzier B, Delemasure S, Talbot S, Ghibu S, Collin B, Sénécal J, Menetrier F, Vergely C, Couture R and L Rochette. Study of oxidative stress and bradykinin receptor activation during doxorubicin-induced cardiomyopathy in rats: effects of the inhibition of Angiotensin-Converting Enzyme. European Cardiology Society. September 2008. Munich, Germany

30.  Talbot S, Dias JP and Couture R. Bradykinin B1 receptor modulation by stimulation of TRPV1: Molecular and Pharmacological evidences. 3rd Annual GRUM meeting. May 29-30th 2008. Montréal, Canada

31.  Delemasure S, Talbot S, Senechal J, Lauzier B, Beausejour CM, Vergely C, de Champlain J, Rochette L and Couture R. Modulation of B1 and B2 kinin receptors during acute anthracyclines-induced cardiotoxicity in mice. Society for Free Radical Biology and Medicine. November 14-18th 2007. Washington, USA

32.  Talbot S, Dias JP, Turmel PT, Carbonneau C, Beausejour CM and Couture R. Expression du récepteur B1 par la stimulation du récepteur TRPV1. 2nd Annual GRUM meeting. June 2007. Montréal, Canada

33.  Turmel PT, Talbot S, Leclerc N, Gaudreau P and Couture R. Expression du récepteur B1 et localisation sur la microglie du rat diabétique. 2nd Annual GRUM meeting. June 2007. Montréal, Canada

34.  Talbot S, Dias JP, de Franca C, Ongali B and Couture R. Allodynie induite par la capsaïcine, une neurotoxine des fibres sensorielles de type C. 2nd Journée de la Pharmacologie. September 2006. Sherbrooke, Canada

35.  Dias JP, Talbot S, de Franca C, Ongali B and Couture R. Allodynie induite par la capsaïcine, une neurotoxine des fibres sensorielles de type C. 4th Congress on ABCD - Journée de la douleur. September 2006. McGill University, Canada

36.  Gallant MA, Slipetz D, Hamelin E, Rochdi MD, Talbot S, Metters KM, de Brum-Fernandes AJ and JL Parent. Characterization of the internalization and desensitization of the Prostaglandin D2 receptors. GPCR Great Lakes Retreat. October 2005. Montebello, Canada

Invited Speaker

 37.  Talbot S, Woolf CJ. Nociceptor neurons drive adaptive immunity. November 2016. Aarhus University, Denmark

38.  Talbot S, Woolf CJ. Nociceptor neurons drive adaptive immunity. June 2016. Université de Montréal, Canada

39.  Talbot S, Woolf CJ. Nociceptor neurons drive adaptive immunity. August 2016. University of Texas, USA

40.  Talbot S, Woolf CJ. Nociceptor neurons drive adaptive immunity. June 2016. Indiana University School of Medicine, USA

41.  Talbot S, Woolf CJ. Nociceptor neurons drive adaptive immunity. May 2016. University of Alberta, Canada

42.  Talbot S, Woolf CJ. Silencing nociceptor neurons reduces allergic airway inflammation. Schepens Eye Research Institute. November 2015. Boston, USA

43.  Talbot S, Woolf CJ. Silencing nociceptor neurons reduces allergic airway inflammation. Neurology department, Harvard Medical School. October 2015. Boston, USA

44.  Talbot S, Couture R. Localization, induction mechanism and pathophysiological role of Kinin B1 receptor in rat model of pain and inflammation. Institute of toxicology and pharmacology of pontifícia universidade do rio grande do sul. September 2011. Porto Alegre, Brazil

45.  Talbot S, Woolf CJ. Silencing nociceptor neurons reduces allergic airway inflammation. F.M. Kirby Neurobiology center. Boston Children’s Hospital. April 2012. Boston, USA

46.  Talbot S, Couture R.  Localization, induction mechanism and pathophysiological role of Kinin B1 receptor in rat model of pain and inflammation. F.M. Kirby neurobiology center of children’s hospital boston. Harvard medical school. August 2011. Boston, USA

47.  Talbot S, Couture R. Localisation, mécanismes d’induction et rôle du récepteur B1 des Kinines. Atelier de travail sur le programme FRSQ-MSSS en médecine transfusionnelle, greffe et biovigilence. April 2008. Montréal, Canada


UPCOMING WORK

1.      Foster SL, Seehus C, Woolf CJ and Talbot S.  Sense and immunity: context-dependent neuro-immune interplay. Frontier in Immunology